Oprah Winfrey aka The Big O visits The David Letterman Show for the first time in sixteen years. If you know anything about the two, they have ahh, let’s just say, interesting relationship. Video inside.

[youtube:http://www.youtube.com/watch?v=VU1ax4OlkBU]

[youtube:http://www.youtube.com/watch?v=JTx5dyDWbDI]

[youtube:http://www.youtube.com/watch?v=rRasZHkBNNk]